Kleihauer-Betke Fetal Stain – Test Update

This will take effect September 24, 2012

Overview and Clinical Utility:

The Kleihauer-Betke Fetal Stain has been discontinued and replaced with Fetal Cell Assay by Flow Cytometry as the routine method to assess fetal-maternal hemorrhage quantification and recommended RhIG dosage.

The traditional slide based Kleihauer-Betke test is a time consuming method with high rates of inter-observer result variation and suboptimal precision.   A more accurate, improved methodology is achieved via the Fetal Cell Assay by Flow Cytometry.

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